DPPA4 antibody (AA 15-304)

Catalog No. ABIN6139802

This Rabbit Polyclonal antibody specifically detects DPPA4 in WB. It exhibits reactivity toward Human.

Quick Overview for DPPA4 antibody (AA 15-304) (ABIN6139802)

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPPA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPPA4 Antibody

Binding Specificity: AA 15-304

Sequence: KGKEWTSTEK SREEDQQASN QPNSIALPGT SAKRTKEKMS IKGSKVLCPK KKAEHTDNPR PQKKIPIPPL PSKLPPVNLI HRDILRAWCQ QLKLSSKGQK LDAYKRLCAF AYPNQKDFPS TAKEAKIRKS LQKKLKVEKG ETSLQSSETH PPEVALPPVG EPPALENSTA LLEGVNTVVV TTSAPEALLA SWARISARAR TPEAVESPQE ASGVRWCVVH GKSLPADTDG WVHLQFHAGQ AWVPEKQEGR VSALFLLPAS NFPPPHLEDN MLCPKCVHRN KVLIKSLQWE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 15-304 of human DPPA4 (NP_060659.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DPPA4

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Alternative Name: DPPA4

Background: This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.,DPPA4,2410091M23Rik,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,DPPA4

Molecular Weight: 33 kDa

Gene ID: 55211

UniProt: Q7L190