LSD1 antibody (AA 97-328)
Quick Overview for LSD1 antibody (AA 97-328) (ABIN5027336)
Target
See all LSD1 (KDM1A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 97-328
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Purification
- Protein A Chromatography
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Immunogen
- A partial length recombinant LSD1 protein (amino acids 97-328) was used as the immunogen for this antibody.
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Isotype
- IgG
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Application Notes
- WB: 0.5-2.0 μg/mL, IHC: 5 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
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Alternative Name
- LSD1
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Background
- LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.
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Molecular Weight
- 115 kDa
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Gene ID
- 23028
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UniProt
- O60341
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
Target
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