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MITF antibody (AA 150-427)

MITF Reactivity: Human WB, IHC Host: Mouse Monoclonal ABM1H91 unconjugated
Catalog No. ABIN5027358
  • Target See all MITF Antibodies
    MITF (Microphthalmia-Associated Transcription Factor (MITF))
    Binding Specificity
    • 20
    • 15
    • 12
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-427
    Reactivity
    • 117
    • 66
    • 26
    • 17
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 92
    • 39
    • 1
    • 1
    Mouse
    Clonality
    • 84
    • 49
    Monoclonal
    Conjugate
    • 64
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MITF antibody is un-conjugated
    Application
    • 71
    • 50
    • 44
    • 35
    • 33
    • 18
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Protein G Chromatography
    Immunogen
    A partial length recombinant MITF protein (amino acids 150-427) was used as the immunogen for this antibody.
    Clone
    ABM1H91
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MITF Primary Antibody
  • Application Notes
    WB: 2-4 μg/mL, IHC: 10 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    MITF (Microphthalmia-Associated Transcription Factor (MITF))
    Alternative Name
    MITF (MITF Products)
    Synonyms
    MITF antibody, ws2a antibody, mitfa antibody, MITF-A antibody, LOC100313655 antibody, mitfb antibody, CMM8 antibody, MI antibody, WS2 antibody, WS2A antibody, bHLHe32 antibody, BCC2 antibody, Bhlhe32 antibody, Gsfbcc2 antibody, Vitiligo antibody, Wh antibody, bw antibody, mi antibody, vit antibody, MITF-H antibody, MITF-M antibody, CMI9 antibody, melanogenesis associated transcription factor antibody, microphthalmia-associated transcription factor antibody, microphthalmia-associated transcription factor S homeolog antibody, Microphthalmia antibody, MITF antibody, mitf antibody, LOC100313655 antibody, mitf.S antibody, LOC100534525 antibody, MICROP antibody, Mitf antibody
    Background
    MITF (Microphthalmia-associated transcription factor) is a basic helix-loop-helix leucine zipper (bHLH-Zip) family factor, involved in lineage-specific pathway regulation of many types of cells including osteoclasts, melanocytes, retinal pigment epithelial cells, mast cells and natural killer cells. It plays a critical role in melanogenesis as a transcriptional activator of tyrosinase, TRP-1, and TRP-2. Moreover, it regulates specification, survival, and proliferation of normal melanocytes, and controls proliferation, migration and invasion of melanoma cells. MITF is the most characterized member of the MIT family, mutations of which can lead to diseases such as Melanoma, Waardenburg syndrome, and Tietz syndrome.
    Molecular Weight
    30 kDa
    Gene ID
    4286
    UniProt
    O75030
    Pathways
    Chromatin Binding
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