TRHR antibody (AA 180-398)

Catalog No. ABIN5027593

The Rabbit Polyclonal anti-TRHR antibody is suitable to detect TRHR in samples from Human. It has been validated for WB.

Quick Overview for TRHR antibody (AA 180-398) (ABIN5027593)

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRHR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRHR Antibody

Binding Specificity: AA 180-398

Purification: Protein A Chromatography

Immunogen: A partial length recombinant TRH-R protein (amino acids 180- 398) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-3 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for TRHR

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Alternative Name: TRH-R

Background: TRH-R (Thyrotropin-releasing hormone (TRH) receptors are Gq/11-protein-coupled receptors) is a member of G-protein coupled receptor 1 family. This is a thyrotropin-releasing hormone receptor. When it binds to TRH, it activates the inositol phospholipid-calcium-protein kinase C transduction pathway. TRH-R also interacts with ACP2acid phosphatase 2. Its expression found mainly in cerebrum, testis during developmental stage. Literature suggests that endogenous TRH and TRH receptor play an important role of a neurotransmission modulation in the brain to control emotional and mental functions.

Molecular Weight: 46 kDa

Gene ID: 7201

UniProt: P34981