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COMT antibody (AA 1-221)

This Mouse Polyclonal antibody specifically detects COMT in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Catalog No. ABIN514522

Quick Overview for COMT antibody (AA 1-221) (ABIN514522)

Target

See all COMT Antibodies
COMT (Catechol-O-Methyltransferase (COMT))

Reactivity

  • 60
  • 49
  • 41
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

  • 71
  • 21
  • 3
  • 1
Mouse

Clonality

  • 66
  • 30
Polyclonal

Conjugate

  • 64
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COMT antibody is un-conjugated

Application

  • 61
  • 42
  • 29
  • 26
  • 24
  • 13
  • 13
  • 9
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-221

    Purpose

    Mouse polyclonal antibody raised against a full-length human COMT protein.

    Sequence

    MGDTKEQRIL NHVLQHAEPG NAQSVLEAID TYCEQKEWAM NVGDKKGKIV DAVIQEHQPS VLLELGAYCG YSAVRMARLL SPGARLITIE INPDCAAITQ RMVDFAGVKD KVTLVVGASQ DIIPQLKKKY DVDTLDMVFL DHWKDRYLPD TLLLEECGLL RKGTVLLADN VICPGAPDFL AHVRGSSCFE CTHYQSFLEY REVVDGLEKA IYKGPGSEAG P

    Cross-Reactivity

    Human

    Characteristics

    Antibody reactive against mammalian transfected lysate.

    Immunogen

    COMT (NP_009294.1, 1 a.a. ~ 221 a.a) full-length human protein.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    No additive

    Preservative

    Without preservative

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hevir, Sinkovec, Rižner: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." in: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).

  • Target

    COMT (Catechol-O-Methyltransferase (COMT))

    Alternative Name

    COMT

    Background

    Full Gene Name: catechol-O-methyltransferase
    Synonyms:

    Gene ID

    1312

    NCBI Accession

    NM_007310

    Pathways

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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