CRH antibody (AA 154-196)

Catalog No. ABIN514593

Cited in 3+ publications. The Mouse Monoclonal anti-CRH antibody (Clone 2B11) (ABIN514593) specifically detects CRH in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CRH antibody (AA 154-196) (ABIN514593)

Target: CRH (Corticotropin Releasing Hormone (CRH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRH antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2B11

Product Details anti-CRH Antibody

Binding Specificity: AA 154-196

Purpose: Mouse monoclonal antibody raised against a partial recombinant CRH.

Sequence: SEEPPISLDL TFHLLREVLE MARAEQLAQQ AHSNRKLMEI IGK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CRH (AAH11031, 154 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CRH antibody (ABIN514593)

Wang, Parobchak, Rosen, Roche, Rosen: "Negative effects of progesterone receptor isoform-A on human placental activity of the noncanonical NF-?B signaling." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E320-8, (2014) (PubMed).

Wang, Palomares, Parobchak, Cece, Rosen, Nguyen, Rosen: "Glucocorticoid receptor signaling contributes to constitutive activation of the noncanonical NF-?B pathway in term human placenta." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 203-11, (2013) (PubMed).

Wang, Parobchak, Rosen: "RelB/NF-?B2 regulates corticotropin-releasing hormone in the human placenta." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 8, pp. 1356-69, (2012) (PubMed).

Target Details for CRH

Target: CRH (Corticotropin Releasing Hormone (CRH))

Alternative Name: CRH

Background: Full Gene Name: corticotropin releasing hormone
Synonyms: CRF

Gene ID: 1392

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour