MDM4-binding Protein antibody (AA 1-490)

Catalog No. ABIN517808

The Mouse Polyclonal anti-MDM4-binding Protein antibody has been validated for WB and IF. It is suitable to detect MDM4-binding Protein in samples from Human. There is 1 publication available.

Quick Overview for MDM4-binding Protein antibody (AA 1-490) (ABIN517808)

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This MDM4-binding Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MDM4-binding Protein Antibody

Binding Specificity: AA 1-490

Purpose: Mouse polyclonal antibody raised against a full-length human MDM4 protein.

Sequence: MTSFSTSAQC STSDSACRIS PGQINQVRPK LPLLKILHAA GAQGEMFTVK EVMHYLGQYI MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTDAAQTL ALAQDHSMDI PSQDQLKQSA EESSTSRKRT TEDDIPTLPT SEHKCIHSRE DEDLIENLAQ DETSRLDLGF EEWDVAGLPW WFLGNLRSNY TPRSNGSTDL QTNQDVGTAI VSDTTDDLWF LNESVSEQLG VGIKVEAADT EQTSEEVGKV SDKKVIEVGK NDDLEDSKSL SDDTDVEVTS EDEWQCTECK KFNSPSKRYC FRCWALRKDW YSDCSKLTHS LSTSDITAIP EKENEGNDVP DCRRTISAPV VRPKDAYIKK ENSKLFDPCN SVEFLDLAHS SESQETISSM GEQLDNLSEQ RTDTENMEDC QNLLKPCSLC EKRPRDGNII HGRTGHLVTC FHCARRLKKA GASCPICKKE IQLVIKVFIA

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: MDM4 (NP_002384.2, 1 a.a. ~ 490 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MDM4-binding Protein antibody (ABIN517808)

Jacob, OBrien, Singh, Comiskey, Littleton, Mohammad, Gladman, Widmann, Jeyaraj, Bolinger, Anderson, Barkauskas, Boris-Lawrie, Chandler: "Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma." in: Neoplasia (New York, N.Y.), Vol. 15, Issue 9, pp. 1049-63, (2013) (PubMed).

Target Details for MDM4-binding Protein

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Alternative Name: MDM4

Background: Full Gene Name: Mdm4 p53 binding protein homolog (mouse)
Synonyms: DKFZp781B1423,HDMX,MDMX,MGC132766,MRP1

Gene ID: 4194

NCBI Accession: NM_002393

Pathways: Cell Division Cycle