ZEB1 antibody (AA 801-900)

Catalog No. ABIN520780

This Mouse Monoclonal antibody specifically detects ZEB1 in WB, ELISA and IF. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for ZEB1 antibody (AA 801-900) (ABIN520780)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 4C4

Product Details anti-ZEB1 Antibody

Binding Specificity: AA 801-900

Purpose: Mouse monoclonal antibody raised against a partial recombinant ZEB1.

Sequence: NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ZEB1 (NP_110378, 801 a.a. ~ 900 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ZEB1 antibody (ABIN520780)

Al-Khalaf, Aboussekhra: "p16(INK4A) induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 985-999, (2016) (PubMed).

Hendrayani, Al-Khalaf, Aboussekhra: "The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1." in: The Journal of biological chemistry, Vol. 289, Issue 45, pp. 30962-76, (2014) (PubMed).

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1

Background: Full Gene Name: zinc finger E-box binding homeobox 1
Synonyms: AREB6,BZP,DELTA-EF1,MGC133261,NIL-2-A,NIL-2A,NIL2A,TCF8,ZEB,ZFHEP,ZFHX1A

Gene ID: 6935

NCBI Accession: NM_030751

Pathways: Regulation of Muscle Cell Differentiation