RIPK2 antibody (AA 431-540)

Catalog No. ABIN522206

The Mouse Monoclonal anti-RIPK2 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect RIPK2 in samples from Human. There is 1 publication available.

Quick Overview for RIPK2 antibody (AA 431-540) (ABIN522206)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RIPK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6F7

Product Details anti-RIPK2 Antibody

Binding Specificity: AA 431-540

Purpose: Mouse monoclonal antibody raised against a partial recombinant RIPK2.

Sequence: LQPGIAQQWI QSKREDIVNQ MTEACLNQSL DALLSRDLIM KEDYELVSTK PTRTSKVRQL LDTTDIQGEE FAKVIVQKLK DNKQMGLQPY PEILVVSRSP SLNLLQNKSM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RIPK2 (AAH04553, 431 a.a. ~ 540 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RIPK2 antibody (ABIN522206)

Yan, Liu: "LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation." in: Protein & cell, Vol. 8, Issue 1, pp. 55-66, (2016) (PubMed).

Target Details for RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Alternative Name: RIPK2

Background: Full Gene Name: receptor-interacting serine-threonine kinase 2
Synonyms: CARD3,CARDIAK,CCK,GIG30,RICK,RIP2

Gene ID: 8767

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades