TSEN34 antibody (C-Term)

Catalog No. ABIN5514423

This Rabbit Polyclonal antibody specifically detects TSEN34 in WB. It exhibits reactivity toward Human.

Quick Overview for TSEN34 antibody (C-Term) (ABIN5514423)

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSEN34 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSEN34 Antibody

Binding Specificity: C-Term

Sequence: PRSALLVQLA TARPRPVKAR PLDWRVQSKD WPHAGRPAHE LRYSIYRDLW

Characteristics: This is a rabbit polyclonal antibody against SEN34. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SEN34

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSEN34

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Alternative Name: SEN34

Background: This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alias Symbols: TSEN34, LENG5, SEN34,

Protein Interaction Partner: UBC, ARMCX3, RAB3GAP2, RAB3GAP1, GNE, BCAR1, GABPA, HNRNPD, Clp1, TSEN15, TSEN54, TSEN2,

Protein Size: 310

Gene ID: 79042

NCBI Accession: NP_076980

UniProt: Q9BSV6