EHHADH antibody (Middle Region)

Catalog No. ABIN5514454

The Rabbit Polyclonal anti-EHHADH antibody is suitable to detect EHHADH in samples from Human. It has been validated for WB.

Quick Overview for EHHADH antibody (Middle Region) (ABIN5514454)

Target: EHHADH (Enoyl-CoA, Hydratase/3-Hydroxyacyl CoA Dehydrogenase (EHHADH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHHADH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EHHADH Antibody

Binding Specificity: Middle Region

Purpose: EHHADH Antibody - middle region

Sequence: VIAVDSDKNQ LATANKMITS VLEKEASKMQ QSGHPWSGPK PRLTSSVKEL

Characteristics: This is a rabbit polyclonal antibody against ECHP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ECHP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76113-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EHHADH

Target: EHHADH (Enoyl-CoA, Hydratase/3-Hydroxyacyl CoA Dehydrogenase (EHHADH))

Alternative Name: EHHADH

Background:

Background Information: The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

Alternative Symbols: LBP, ECHD, LBFP, MFE1, PBFE, FRTS3, L-PBE

Protein Name: peroxisomal bifunctional enzyme

Molecular Weight: 79kDa

Gene ID: 1962

NCBI Accession: NP_001957

UniProt: Q08426

Pathways: Monocarboxylic Acid Catabolic Process