ALDH8A1 antibody (C-Term)

Catalog No. ABIN5514490

The Rabbit Polyclonal anti-ALDH8A1 antibody is suitable to detect ALDH8A1 in samples from Human. It has been validated for WB.

Quick Overview for ALDH8A1 antibody (C-Term) (ABIN5514490)

Target: ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH8A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH8A1 Antibody

Binding Specificity: C-Term

Sequence: KKLQSGLVWT NCWLIRELNL PFGGMKSSGI GREGAKDSYD FFTEIKTITV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH8A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH8A1

Target: ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))

Alternative Name: ALDH8A1

Background: This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.

Alias Symbols: ALDH12, DJ352A20.2

Protein Size: 487

Gene ID: 64577

NCBI Accession: NM_001193480, NP_001180409

UniProt: Q9H2A2