Arhgef9 antibody (C-Term)

Catalog No. ABIN5514508

The Rabbit Polyclonal anti-Arhgef9 antibody is suitable to detect Arhgef9 in samples from Human. It has been validated for WB.

Quick Overview for Arhgef9 antibody (C-Term) (ABIN5514508)

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arhgef9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Arhgef9 Antibody

Binding Specificity: C-Term

Sequence: VPKQKGVNSA RSVPPSYPPP QDPLNHGQYL VPDGIAQSQV FEFTEPKRSQ

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Arhgef9

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Alternative Name: ARHGEF9

Background: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PEM2, EIEE8, PEM-2, HPEM-2, COLLYBISTIN

Protein Size: 167

Gene ID: 23229

NCBI Accession: NM_001173479, NP_001166950

UniProt: O43307

Pathways: Neurotrophin Signaling Pathway