ATP7B antibody (Middle Region)
Quick Overview for ATP7B antibody (Middle Region) (ABIN5514518)
Target
See all ATP7B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- IIMSTLTLVV WIVIGFIDFG VVQRYFPNPN KHISQTEVII RFAFQTSITV
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Predicted Reactivity
- Dog: 82%, Guinea Pig: 82%, Horse: 82%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 91%
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Characteristics
- This is a rabbit polyclonal antibody against ATP7B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ATP7B
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anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 59-426) antibody
ATP7B Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 1361-1391), (C-Term) antibodyATP7B Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB19038 unconjugated
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 1372-1465) antibodyATP7B Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E10 unconjugated
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (PerCP)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 PerCP
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (Atto 390)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 Atto 390
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (Atto 488)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 Atto 488
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (HRP)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 HRP
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (FITC)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 FITC
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (Atto 594)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 Atto 594
anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 3-21) antibody (Biotin)ATP7B Reactivity: Human WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S62-29 Biotin
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
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Alternative Name
- ATP7B
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Background
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This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Alias Symbols: WD, PWD, WC1, WND
Protein Size: 676 -
Gene ID
- 540
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NCBI Accession
- NM_000053, NP_000044
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UniProt
- P35670
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Pathways
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
Target
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