Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) antibody

Catalog No. ABIN5514539

The Rabbit Polyclonal anti-Neural Wiskott-Aldrich syndrome protein antibody (ABIN5514539) specifically detects Neural Wiskott-Aldrich syndrome protein in WB. The antibody is reactive with Human samples.

Quick Overview for Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) antibody (ABIN5514539)

Target: Neural Wiskott-Aldrich syndrome protein (WASL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: WASL Antibody - N-terminal region

Sequence: FANEEEAKKF RKAVTDLLGR RQRKSEKRRD PPNGPNLPMA TVDIKNPEIT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WASL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63497-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Neural Wiskott-Aldrich syndrome protein (WASL)

Alternative Name: WASL

Background:

Background Information: This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.

Gene Name: Wiskott-Aldrich syndrome-like

Alternative Symbols: NWASP, WASPB, N-WASP

Protein Name: neural Wiskott-Aldrich syndrome protein

Molecular Weight: 55 kDa

Gene ID: 8976

NCBI Accession: NP_003932

UniProt: O00401