BMF antibody (N-Term)

Catalog No. ABIN5514556

The Rabbit Polyclonal anti-BMF antibody is suitable to detect BMF in samples from Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for BMF antibody (N-Term) (ABIN5514556)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMF Antibody

Binding Specificity: N-Term

Purpose: BMF Antibody - N-terminal region

Sequence: MEPSQCVEEL EDDVFQPEDG EPVTQPGSLL SADLFAQSLL DCPLSRLQLF

Predicted Reactivity: Cow: 92%, Dog: 92%, Goat: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against BMF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43597-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Alternative Name: BMF

Background:

Background Information: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Bcl2 modifying factor

Alternative Symbols: BMF,

Protein Name: Bcl-2-modifying factor

Molecular Weight: 14kDa

Gene ID: 90427

UniProt: Q96LC9