F162A antibody (N-Term)

Catalog No. ABIN5514584

The Rabbit Polyclonal anti-F162A antibody (ABIN5514584) specifically detects F162A in WB. The antibody is reactive with Human samples.

Quick Overview for F162A antibody (N-Term) (ABIN5514584)

Target: F162A (FAM162A) (Family with Sequence Similarity 162, Member A (FAM162A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F162A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-F162A Antibody

Binding Specificity: N-Term

Sequence: SLRLTRSSDL KRINGFCTKP QESPGAPSRT YNRVPLHKPT DWQKKILIWS

Characteristics: This is a rabbit polyclonal antibody against F162A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human F162A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for F162A

Target: F162A (FAM162A) (Family with Sequence Similarity 162, Member A (FAM162A))

Alternative Name: F162A

Background: F162A is proposed to be involved in regulation of apoptosis, the exact mechanism may differ between cell types/tissues. It may be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. It may be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus, however, the involvement of caspases has been reported conflictingly.

Alias Symbols: FAM162A, C3orf28, E2IG5, DC16, FWP001,

Protein Interaction Partner: UBC, TIMM23B, ADRB2, HSP90AA1, UBL4A, PTRF, IWS1, RMDN3, SRRT, MRPL22, HACL1, TM9SF4, VDAC2, SSR3, SLC25A1,

Protein Size: 154

Gene ID: 26355

NCBI Accession: NP_055182

UniProt: Q96A26

Pathways: Positive Regulation of Endopeptidase Activity, SARS-CoV-2 Protein Interactome