COMP antibody (N-Term)

Catalog No. ABIN5514649

The Rabbit Polyclonal anti-COMP antibody is suitable to detect COMP in samples from Mouse, Human, Rat, Dog, Horse, Pig, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for COMP antibody (N-Term) (ABIN5514649)

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Reactivity: Mouse, Human, Rat, Dog, Horse, Pig, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COMP Antibody

Binding Specificity: N-Term

Sequence: CVLLLTLAAL GASGQGQSPL GSDLGPQMLR ELQETNAALQ DVRELLRQQV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against COMP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COMP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COMP

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Alternative Name: COMP

Background: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Alias Symbols: COMP,

Protein Interaction Partner: OTX1, FN1, COL9A1, COL2A1,

Protein Size: 757

Gene ID: 1311

NCBI Accession: NP_000086

UniProt: P49747