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Phospholipase C gamma 2 antibody (Middle Region)
PLCG2
Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Phospholipase C gamma 2 Antibody
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Target
See all Phospholipase C gamma 2 (PLCG2) Antibodies
Phospholipase C gamma 2 (PLCG2)
Binding Specificity
All epitopes for Phospholipase C gamma 2 antibodies
Middle Region
Reactivity
All reactivities for Phospholipase C gamma 2 antibodies
Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig
Host
All hosts for Phospholipase C gamma 2 antibodies
Rabbit
Clonality
All clonalities for Phospholipase C gamma 2 antibodies
Polyclonal
Conjugate
All conjugates for Phospholipase C gamma 2 antibodies
This Phospholipase C gamma 2 antibody is un-conjugated
Application
All applications for Phospholipase C gamma 2 antibodies
Western Blotting (WB)
Sequence
ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against PLCG2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Phospholipase C gamma 2
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Target
Phospholipase C gamma 2 (PLCG2)
Alternative Name
PLCG2 (PLCG2 Products )
Synonyms
PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
Background
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Alias Symbols: PLCG2, Protein Interaction Partner: UBC, ZNF512B, ERBB2, EGFR, PRKCA, PLD1, IRS1, BLNK, LAT2, LIME1, GAB2, DAPP1, PRKD1, CBLB, GAB1, KHDRBS1, LAT, SH3BP2, LCP2, TEC, SHC1, PLCG2, SYK, BTK, KDR, BLK, ITK, LYN, FLT1, NPM1, LCK, JAK2, JAK1, FCER1G, HCK, FYN, EPOR, CD19, PLXNB1, VAV1, PTPN11, Protein Size: 1265
Gene ID
5336
NCBI Accession
NM_002661 , NP_002652
UniProt
P16885
Pathways
RTK Signaling , WNT Signaling , Fc-epsilon Receptor Signaling Pathway , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Toll-Like Receptors Cascades , VEGF Signaling , BCR Signaling
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