GLB1 antibody (C-Term)

Catalog No. ABIN5514746

The Rabbit Polyclonal anti-GLB1 antibody (ABIN5514746) specifically detects GLB1 in WB. The antibody is reactive with Human samples.

Quick Overview for GLB1 antibody (C-Term) (ABIN5514746)

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLB1 Antibody

Binding Specificity: C-Term

Purpose: GLB1 Antibody - C-terminal region

Sequence: APCSSDDPEL CAVTFVDRPV IGSSVTYDHP SKPVEKRLMP PPPQKNKDSW

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GLB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81168-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLB1

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Alternative Name: GLB1

Background:

Background Information: This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome.

Gene Name: galactosidase beta 1

Alternative Symbols: EBP, ELNR1, MPS4B

Protein Name: beta-galactosidase

Molecular Weight: 60 kDa

Gene ID: 2720

NCBI Accession: NP_000395

UniProt: P16278

Pathways: Glycosaminoglycan Metabolic Process