FANCI antibody (C-Term)

Catalog No. ABIN5514761

The Rabbit Polyclonal anti-FANCI antibody (ABIN5514761) specifically detects FANCI in WB. The antibody is reactive with Human samples.

Quick Overview for FANCI antibody (C-Term) (ABIN5514761)

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FANCI Antibody

Binding Specificity: C-Term

Purpose: FANCI Antibody - C-terminal region

Sequence: MQHMKLSTSR DFKIKGNILD MVLREDGEDE NEEGTASEHG GQNKEPAKKK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FANCI

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73956-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Alternative Name: FANCI

Background:

Background Information: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Gene Name: Fanconi anemia complementation group I

Alternative Symbols: KIAA1794

Protein Name: Fanconi anemia group I protein

Molecular Weight: 139 kDa

Gene ID: 55215

NCBI Accession: NP_001106849

UniProt: Q9NVI1

Pathways: DNA Damage Repair