MAPK6 antibody (N-Term)

Catalog No. ABIN5514796

The Rabbit Polyclonal anti-MAPK6 antibody is suitable to detect MAPK6 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig and Guinea Pig. It has been validated for WB.

Quick Overview for MAPK6 antibody (N-Term) (ABIN5514796)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK6 Antibody

Binding Specificity: N-Term

Sequence: LDHDNIVKVF EILGPSGSQL TDDVGSLTEL NSVYIVQEYM ETDLANVLEQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MK06. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MK06

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: MK06

Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

Alias Symbols: MAPK6, ERK3, PRKM6,

Protein Interaction Partner: MAPKAPK5, AURKA, HERC2, NEURL4, PSMA7, MAPK6, A2M, EIF2S3, EGLN3, vif, GALNT7, MBIP, SLC20A1, JUNB, KDSR, CCND3, ELAVL1, UBE3A, UBC, FOXO3, EMD, EIF4A1, EEF1A2, PHC2, DKC1, DDOST, DBN1, CNTN1, CFL1, CDH13, CASP6, CALR, DDR1, CA12, CA1, ATP5J, ARHGDIA, APO

Protein Size: 721

Gene ID: 5597

NCBI Accession: XP_005254596

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C