S100A6 antibody (N-Term)

Catalog No. ABIN5514810

This Rabbit Polyclonal antibody specifically detects S100A6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Dog, Pig, Cow and Horse.

Quick Overview for S100A6 antibody (N-Term) (ABIN5514810)

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S100A6 Antibody

Binding Specificity: N-Term

Sequence: LSKKELKELI QKELTIGSKL QDAEIARLME DLDRNKDQEV NFQEYVTFLG

Predicted Reactivity: Cow: 82%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against S10A6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human S10A6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S10A6

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Alias Symbols: S100A6, CACY,

Protein Interaction Partner: UBC, PEX5, PPID, FKBP4, STUB1, CLNS1A, DHX36, TOM1L2, SEC24A, SEC23A, CD2BP2, NUP214, CACYBP, CDK2, SUMO2, MDM2, SUGT1, ANXA11, S100B, ANXA2, GAPDH, S100A6,

Protein Size: 90

Gene ID: 6277

NCBI Accession: NP_055439

UniProt: P06703

Pathways: S100 Proteins