Glutathione Synthetase antibody (C-Term)

Catalog No. ABIN5514831

Product Details anti-Glutathione Synthetase Antibody

Target: Glutathione Synthetase (GSS)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEGDQAIAEA LAAPSRFVLK PQREGGGNNL YGEEMVQALK QLKDSEERAS

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GSS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GSS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS (GSS Products)

Synonyms: PRNP antibody, 6835 antibody, CG32497 antibody, CG33065 antibody, CG6835 antibody, Dmel\\CG6835 antibody, F21A20.90 antibody, F21A20_90 antibody, GLUTATHIONE SYNTHETASE antibody, GSHB antibody, glutathione synthetase 2 antibody, GSHS antibody, AI314904 antibody, GS-A/GS-B antibody, gssls-a antibody, glutathione synthetase antibody, Glutathione Synthetase antibody, glutathione synthetase 2 antibody, glutathione synthetase L homeolog antibody, GSS antibody, GSH2 antibody, Tola_1250 antibody, PC1_3711 antibody, Dd586_3633 antibody, Kvar_0701 antibody, Alvin_0197 antibody, Nhal_0215 antibody, BC1002_0254 antibody, Cseg_4017 antibody, Snov_3844 antibody, Aazo_1904 antibody, M301_2613 antibody, Bresu_0515 antibody, Isop_1460 antibody, Marme_4020 antibody, Thicy_0325 antibody, Sinme_3668 antibody, Mesop_0757 antibody, Gss antibody, gss.L antibody

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Alias Symbols: GSS,

Protein Interaction Partner: GSS, UBC, GINS3, OLA1, DCPS, ABHD14A, RRAGB, PDIA4, USP14, YWHAH, YWHAG, YWHAE, YWHAB, VCL, RAP1GDS1, PPP5C, PAFAH1B2, MVK, MSN, HMGB3, ECHS1, TBCB, ASS1, ASNS, CDK9, TERF1, GSTZ1,

Protein Size: 474

Gene ID: 2937

NCBI Accession: XP_005260463

UniProt: P48637

Pathways: Warburg Effect