HIP1 antibody (C-Term)

Catalog No. ABIN5514846

Product Details anti-HIP1 Antibody

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IVESGRGTAS PKEFYAKNSR WTEGLISASK AVGWGATVMV DAADLVVQGR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against HIP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1 (HIP1 Products)

Synonyms: HIP-I antibody, ILWEQ antibody, CG10971 antibody, Dmel\\CG10971 antibody, Hip1R antibody, 2610109B09Rik antibody, A930014B11Rik antibody, E130315I21Rik antibody, mKIAA4113 antibody, huntingtin interacting protein 1 antibody, Huntingtin interacting protein 1 antibody, HIP1 antibody, Hip1 antibody, hip1 antibody

Background: The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain, this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.

Alias Symbols: HIP1,

Protein Interaction Partner: DAZAP2, REL, HIP1, FBXO25, CLTC, BFAR, ITSN1, UBC, MAPK6, HTT, HIP1R, IFT57, PFDN1, RPS10, EIF6, CASP9, APAF1, CASP8, AP2A1, AP2B1, CASP3, CLTB, CLTA, TFAP2A,

Protein Size: 1037

Gene ID: 3092

NCBI Accession: NP_005329

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity