HIP1 antibody (N-Term)

Catalog No. ABIN5514847

The Rabbit Polyclonal anti-HIP1 antibody is suitable to detect HIP1 in samples from Human. It has been validated for WB.

Quick Overview for HIP1 antibody (N-Term) (ABIN5514847)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIP1 Antibody

Binding Specificity: N-Term

Purpose: HIP1 Antibody - N-terminal region

Sequence: SQQNLFDNKF DDIFGSSFSS DPFNFNSQNG VNKDEKDHLI ERLYREISGL

Characteristics: This is a rabbit polyclonal antibody against HIP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72597-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1

Background:

Background Information: The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain, this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.

Alternative Symbols: SHON, HIP-I, ILWEQ, SHONbeta, SHONgamma

Molecular Weight: 108kDa

Gene ID: 3092

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity