IL-33 antibody (C-Term)

Catalog No. ABIN5514901

The Rabbit Polyclonal anti-IL-33 antibody is suitable to detect IL-33 in samples from Human. It has been validated for WB.

Quick Overview for IL-33 antibody (C-Term) (ABIN5514901)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-33 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-33 Antibody

Binding Specificity: C-Term

Purpose: IL33 Antibody - C-terminal region

Sequence: KKDKVLLSYY ESQHPSNESG DGVDGKMLMV TLSPTKDFWL HANNKEHSVE

Characteristics: This is a rabbit polyclonal antibody against IL33. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL33

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74588-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Alternative Name: IL33

Background:

Background Information: IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4, MIM 147780). IL33 is a ligand for IL33R (IL1RL1, MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells.

Alternative Symbols: DVS27, IL1F11, NF-HEV, NFEHEV, C9orf26

Molecular Weight: 29 kDa

Gene ID: 90865

NCBI Accession: XP_005251684

UniProt: O95760

Pathways: Production of Molecular Mediator of Immune Response