Prolactin Receptor antibody (C-Term)

Catalog No. ABIN5515078

The Rabbit Polyclonal anti-Prolactin Receptor antibody is suitable to detect Prolactin Receptor in samples from Human. It has been validated for WB.

Quick Overview for Prolactin Receptor antibody (C-Term) (ABIN5515078)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Prolactin Receptor Antibody

Binding Specificity: C-Term

Purpose: PRLR Antibody - C-terminal region

Sequence: DGALSLLPKQ RENSGKPKKP GTPENNKEYA KVSGVMDNNI LVLVPDPHAK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRLR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80729-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background:

Background Information: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Gene Name: prolactin receptor

Alternative Symbols: HPRL, MFAB, hPRLrI, RI-PRLR

Protein Name: prolactin receptor

Molecular Weight: 68 kDa

Gene ID: 5618

NCBI Accession: NP_000940

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus