Prolactin Receptor antibody (Middle Region)

Catalog No. ABIN5515079

The Rabbit Polyclonal anti-Prolactin Receptor antibody (ABIN5515079) specifically detects Prolactin Receptor in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Rabbit, Dog, Goat, Guinea Pig, Horse, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for Prolactin Receptor antibody (Middle Region) (ABIN5515079)

Target: Prolactin Receptor (PRLR)

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Prolactin Receptor Antibody

Binding Specificity: Middle Region

Sequence: WAVALKGYSM VTCIFPPVPG PKIKGFDAHL LEKGKSEELL SALGCQDFPP

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PRLR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRLR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Alias Symbols: PRLR,

Protein Interaction Partner: UBC, BTRC, STAT5B, PRLR, JAK2, CREBBP, FBXW11, CSH1, PRL, YWHAG, SOCS2, SOCS3, NEK3, CISH, YWHAZ, GHR, TEC, VAV2, ZAP70, PTPN11, VAV1, GH1, PPIA, GTF3A,

Protein Size: 622

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus