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Prolactin Receptor antibody (Middle Region)
PRLR
Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Prolactin Receptor Antibody
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Target
See all Prolactin Receptor (PRLR) Antibodies
Prolactin Receptor (PRLR)
Binding Specificity
All epitopes for Prolactin Receptor antibodies
Middle Region
Reactivity
All reactivities for Prolactin Receptor antibodies
Human, Rat, Mouse, Cow, Rabbit, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)
Host
All hosts for Prolactin Receptor antibodies
Rabbit
Clonality
All clonalities for Prolactin Receptor antibodies
Polyclonal
Conjugate
All conjugates for Prolactin Receptor antibodies
This Prolactin Receptor antibody is un-conjugated
Application
All applications for Prolactin Receptor antibodies
Western Blotting (WB)
Sequence
WAVALKGYSM VTCIFPPVPG PKIKGFDAHL LEKGKSEELL SALGCQDFPP
Predicted Reactivity
Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against PRLR. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PRLR
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Prolactin Receptor
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Target
Prolactin Receptor (PRLR)
Alternative Name
PRLR (PRLR Products )
Synonyms
hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody
Background
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. Alias Symbols: PRLR, Protein Interaction Partner: UBC, BTRC, STAT5B, PRLR, JAK2, CREBBP, FBXW11, CSH1, PRL, YWHAG, SOCS2, SOCS3, NEK3, CISH, YWHAZ, GHR, TEC, VAV2, ZAP70, PTPN11, VAV1, GH1, PPIA, GTF3A, Protein Size: 622
Gene ID
5618
UniProt
P16471
Pathways
JAK-STAT Signaling , Response to Growth Hormone Stimulus
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