RASA3 antibody (N-Term)

Catalog No. ABIN5515101

This Rabbit Polyclonal antibody specifically detects RASA3 in WB. It exhibits reactivity toward Human.

Quick Overview for RASA3 antibody (N-Term) (ABIN5515101)

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASA3 Antibody

Binding Specificity: N-Term

Purpose: RASA3 Antibody - N-terminal region

Sequence: YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL

Characteristics: This is a rabbit polyclonal antibody against RASA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74174-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Alternative Name: RASA3

Background:

Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Alternative Symbols: GAPIII, GAP1IP4BP

Molecular Weight: 91kDa

Gene ID: 22821

NCBI Accession: NP_031394

UniProt: Q14644