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RASA3 antibody (N-Term)
RASA3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RASA3 Antibody
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Target
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RASA3
(RAS P21 Protein Activator 3 (RASA3))
Binding Specificity
All epitopes for RASA3 antibodies
N-Term
Reactivity
All reactivities for RASA3 antibodies
Human
Host
All hosts for RASA3 antibodies
Rabbit
Clonality
All clonalities for RASA3 antibodies
Polyclonal
Conjugate
All conjugates for RASA3 antibodies
This RASA3 antibody is un-conjugated
Application
All applications for RASA3 antibodies
Western Blotting (WB)
Sequence
YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL
Characteristics
This is a rabbit polyclonal antibody against RASA3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for RASA3
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Target
RASA3
(RAS P21 Protein Activator 3 (RASA3))
Alternative Name
RASA3 (RASA3 Products )
Synonyms
rasa3 antibody, MGC82492 antibody, RASA3 antibody, gapiii antibody, gap1ip4bp antibody, LOC100222817 antibody, GAP1IP4BP antibody, GAPIII antibody, AI326412 antibody, C86362 antibody, E130011G04 antibody, scat antibody, R-ras gap antibody, RAS p21 protein activator 3 L homeolog antibody, RAS p21 protein activator 3 antibody, ras GTPase-activating protein 3 antibody, rasa3.L antibody, RASA3 antibody, rasa3 antibody, LOC100433573 antibody, Rasa3 antibody
Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. Alias Symbols: RASA3, Protein Interaction Partner: UBC, ARHGAP19, SPTB, APP, FES, RAP1A, GNB2L1, HCK, Protein Size: 834
Gene ID
22821
NCBI Accession
NP_031394
UniProt
Q14644
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