SNIP1 antibody (C-Term)

Catalog No. ABIN5515142

The Rabbit Polyclonal anti-SNIP1 antibody (ABIN5515142) specifically detects SNIP1 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for SNIP1 antibody (C-Term) (ABIN5515142)

Target: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNIP1 Antibody

Binding Specificity: C-Term

Purpose: SNIP1 Antibody - C-terminal region

Sequence: GNGTFLNNKR IEPQRYYELK EKDVLKFGFS SREYVLLHES SDTSEIDRKD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SNIP1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33584-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNIP1

Target: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Alternative Name: SNIP1

Background:

Background Information: This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).

Gene Name: Smad nuclear interacting protein 1

Alternative Symbols: PML1, PMRED

Protein Name: Smad nuclear-interacting protein 1

Molecular Weight: 43kDa

Gene ID: 79753

NCBI Accession: NP_078976

UniProt: Q8TAD8

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection