SNIP1 antibody (C-Term)
Quick Overview for SNIP1 antibody (C-Term) (ABIN5515142)
Target
See all SNIP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- GNGTFLNNKR IEPQRYYELK EKDVLKFGFS SREYVLLHES SDTSEIDRKD
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Characteristics
- This is a rabbit polyclonal antibody against SNIP1. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNIP1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))
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Alternative Name
- SNIP1
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Background
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This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
Alias Symbols: SNIP1,
Protein Interaction Partner: CLK2, TNIP1, SUMO1, SUMO2, TTC14, PRPF40A, C17orf85, ZCCHC10, SRRM2, SF3B1, SNW1, CHERP, PRPF3, UBC, SRPK2, MFAP1, IK, CDK6, MYC, MAX, ATR, RELA, GMEB1, PIAS1, ZCCHC7, TOPORS, ZNF451, ZMYM5, UBE2I, PIAS2, PIAS4, SP100, SETDB1, HIPK1, FAF1, HIPK3, EIF3C, E
Protein Size: 396 -
Gene ID
- 79753
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NCBI Accession
- NP_078976
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UniProt
- Q8TAD8
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Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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