SF3A2 antibody (N-Term)

Catalog No. ABIN5515335

This Rabbit Polyclonal antibody specifically detects SF3A2 in WB. It exhibits reactivity toward Human.

Quick Overview for SF3A2 antibody (N-Term) (ABIN5515335)

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SF3A2 Antibody

Binding Specificity: N-Term

Purpose: SF3A2 Antibody - N-terminal region

Sequence: GGKTGSGGVA SSSESNRDRR ERLRQLALET IDINKDPYFM KNHLGSYECK

Characteristics: This is a rabbit polyclonal antibody against SF3A2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SF3A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73890-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SF3A2

Background:

Background Information: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Alternative Symbols: PRP11, SAP62, PRPF11, SF3a66

Molecular Weight: 51kDa

Gene ID: 8175

NCBI Accession: NP_009096

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization