SF3A2 antibody (N-Term)

Catalog No. ABIN5515335

Product Details anti-SF3A2 Antibody

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GGKTGSGGVA SSSESNRDRR ERLRQLALET IDINKDPYFM KNHLGSYECK

Characteristics: This is a rabbit polyclonal antibody against SF3A2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SF3A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SF3A2 (SF3A2 Products)

Synonyms: SAP62 antibody, SF3a66 antibody, sf3a2 antibody, MGC52805 antibody, prp11 antibody, prpf11 antibody, sap62 antibody, sf3a66 antibody, SF3A2 antibody, 66kDa antibody, AW047242 antibody, PRP11 antibody, SFA66 antibody, Sap62 antibody, PRPF11 antibody, splicing factor 3a subunit 2 antibody, splicing factor 3a subunit 2 S homeolog antibody, splicing factor 3a, subunit 2 antibody, SF3A2 antibody, sf3a2.S antibody, sf3a2 antibody, Sf3a2 antibody

Background: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Alias Symbols: SF3A2, SAP62,

Protein Interaction Partner: UBC, WWOX, rev, PRPF40A, WBP4, TCERG1, APBB1, HECW2, PAN2, SMURF2, SF3A1, PRPF31, NIPBL, SF3B1, SF3B3, SF3B2, SF3A3, PRPF8, PPIE, PRPF3, SART1, TPM3, SNRPA1, SUMO1, SUMO3, CUL3, ISG15, RBM17, PHF5A, NRIP2, SF3B5, C19orf43, PQBP1, DDX46, RBM39, DDX23, EFTU

Protein Size: 464

Gene ID: 8175

NCBI Accession: NP_009096

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization