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ARHGDIB antibody (N-Term)
ARHGDIB
Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ARHGDIB Antibody
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Target
See all ARHGDIB Antibodies
ARHGDIB
(rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
Binding Specificity
All epitopes for ARHGDIB antibodies
N-Term
Reactivity
All reactivities for ARHGDIB antibodies
Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
Host
All hosts for ARHGDIB antibodies
Rabbit
Clonality
All clonalities for ARHGDIB antibodies
Polyclonal
Conjugate
All conjugates for ARHGDIB antibodies
This ARHGDIB antibody is un-conjugated
Application
All applications for ARHGDIB antibodies
Western Blotting (WB)
Sequence
MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK
Predicted Reactivity
Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
Characteristics
This is a rabbit polyclonal antibody against ARHGDIB. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGDIB
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ARHGDIB
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Target
ARHGDIB
(rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
Alternative Name
ARHGDIB (ARHGDIB Products )
Synonyms
ARHGDIB antibody, zgc:65966 antibody, arhgdib antibody, MGC69067 antibody, gdia2 antibody, rhodgi-2 antibody, rhodgi2 antibody, D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, Gdid4 antibody, Rho GDP dissociation inhibitor (GDI) gamma antibody, Rho GDP dissociation inhibitor (GDI) beta S homeolog antibody, Rho GDP dissociation inhibitor beta antibody, Rho GDP dissociation inhibitor (GDI) beta antibody, Rho, GDP dissociation inhibitor (GDI) beta antibody, arhgdig antibody, arhgdib.S antibody, ARHGDIB antibody, arhgdib antibody, Arhgdib antibody
Background
Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. Alias Symbols: D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Protein Interaction Partner: ZBTB1, Rabgef1, Rab6a, APP, UBC, UFM1, RAC3, RAC1, RAC2, RHOH, CASP3, RHOA, VAV1, EZR, CDC42, CUL3, KLHL12, Protein Size: 201
Gene ID
397
NCBI Accession
NM_001175 , NP_001166
UniProt
P52566
Pathways
Caspase Cascade in Apoptosis
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