IL1A antibody (N-Term)

Catalog No. ABIN5515428

This Rabbit Polyclonal antibody specifically detects IL1A in WB. It exhibits reactivity toward Human, Rat, Mouse, Goat and Rabbit.

Quick Overview for IL1A antibody (N-Term) (ABIN5515428)

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human, Rat, Mouse, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL1A Antibody

Binding Specificity: N-Term

Sequence: VPDMFEDLKN CYSENEEDSS SIDHLSLNQK SFYHVSYGPL HEGCMDQSVS

Predicted Reactivity: Goat: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IL1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Alias Symbols: IL1A, IL1F1,

Protein Size: 271

Gene ID: 3552

NCBI Accession: NP_000566

UniProt: P01583

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints