ALKBH2 antibody (C-Term)

Catalog No. ABIN5515460

Product Details anti-ALKBH2 Antibody

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DHVSGVTGQT FNFVLINRYK DGCDHIGEHR DDERELAPGS PIASVSFGAC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ALKB2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-ALKBH2 antibody is: synthetic peptide directed towards the C-terminal region of Human ALKB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALKBH2

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Alternative Name: ALKBH2 (ALKBH2 Products)

Background: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]

Alias Symbols: ABH2

Protein Interaction Partner: UBC,

Protein Size: 261

Gene ID: 121642

UniProt: Q6NS38

Pathways: DNA Damage Repair