LTBR antibody (C-Term)

Catalog No. ABIN5515510

The Rabbit Polyclonal anti-LTBR antibody is suitable to detect LTBR in samples from Human. It has been validated for WB.

Quick Overview for LTBR antibody (C-Term) (ABIN5515510)

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LTBR Antibody

Binding Specificity: C-Term

Sequence: IYNGPVLGGP PGPGDLPATP EPPYPIPEEG DPGPPGLSTP HQEDGKAWHL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LTBR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Alternative Name: LTBR

Background: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alias Symbols: CD18, TNFCR, TNFR3, D12S370, TNFR-RP, TNFRSF3, TNFR2-RP, LT-BETA-R, TNF-R-III

Protein Size: 435

Gene ID: 4055

NCBI Accession: NM_001270987, NP_001257916

UniProt: P36941

Pathways: NF-kappaB Signaling