STON1 antibody (N-Term)

Catalog No. ABIN5515689

This Rabbit Polyclonal antibody specifically detects STON1 in WB. It exhibits reactivity toward Human.

Quick Overview for STON1 antibody (N-Term) (ABIN5515689)

Target: STON1 (Stonin 1 (STON1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STON1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STON1 Antibody

Binding Specificity: N-Term

Purpose: STON1 Antibody - N-terminal region

Sequence: PSGSSSTSST PLSSPIVDFY FSPGPPSNSP LSTPTKDFPG FPGIPKAGTH

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STON1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75395-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for STON1

Target: STON1 (Stonin 1 (STON1))

Alternative Name: STON1

Background:

Background Information: Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants.

Gene Name: stonin 1

Alternative Symbols: SALF, SBLF, STN1, STNB1

Protein Name: stonin-1

Molecular Weight: 81 kDa

Gene ID: 11037

NCBI Accession: NP_001185524

UniProt: Q9Y6Q2