BOK antibody (N-Term)

Catalog No. ABIN5515825

The Rabbit Polyclonal anti-BOK antibody is suitable to detect BOK in samples from Human, Mouse, Rat, Cow, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for BOK antibody (N-Term) (ABIN5515825)

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BOK Antibody

Binding Specificity: N-Term

Sequence: AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERAAPVP

Predicted Reactivity: Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against BOK. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BOK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BOK

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Alternative Name: BOK

Background: The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Alias Symbols: BOK, BCL2L9,

Protein Interaction Partner: MYC, UBC, NOA1, MCL1, BCL2A1,

Protein Size: 212

Gene ID: 666

NCBI Accession: XP_005247094

UniProt: Q9UMX3

Pathways: Positive Regulation of Endopeptidase Activity