CCDC46 antibody (N-Term)

Catalog No. ABIN5515859

The Rabbit Polyclonal anti-CCDC46 antibody (ABIN5515859) specifically detects CCDC46 in WB. The antibody is reactive with Human samples.

Quick Overview for CCDC46 antibody (N-Term) (ABIN5515859)

Target: CCDC46 (Coiled-Coil Domain Containing 46 (CCDC46))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC46 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCDC46 Antibody

Binding Specificity: N-Term

Purpose: CEP112 Antibody - N-terminal region

Sequence: FDEPNPARAK GSSPEGLPAW VLGELETSEH KLNESWKLSS GEDNTLVQSP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEP112

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78865-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCDC46

Target: CCDC46 (Coiled-Coil Domain Containing 46 (CCDC46))

Alternative Name: CEP112

Background:

Background Information: This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants.

Gene Name: centrosomal protein 112 kDa

Alternative Symbols: CCDC46, MACOCO, SPGF44

Protein Name: centrosomal protein of 112 kDa

Molecular Weight: 62 kDa

Gene ID: 201134

NCBI Accession: NP_001032402

UniProt: J3QQV3

Pathways: SARS-CoV-2 Protein Interactome