MARK4 antibody (N-Term)

Catalog No. ABIN5516101

The Rabbit Polyclonal anti-MARK4 antibody is suitable to detect MARK4 in samples from Human. It has been validated for WB.

Quick Overview for MARK4 antibody (N-Term) (ABIN5516101)

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MARK4 Antibody

Binding Specificity: N-Term

Purpose: MARK4 Antibody - N-terminal region

Sequence: GNDRNSDTHG TLGSGRSSDK GPSWSSRSLG ARCRNSIASC PEEQPHVGNY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MARK4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77597-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARK4

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Alternative Name: MARK4

Background:

Background Information: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: MAP/microtubule affinity-regulating kinase 4

Alternative Symbols: MARK4L, MARK4S, MARKL1, PAR-1D, MARKL1L

Protein Name: MAP/microtubule affinity-regulating kinase 4

Molecular Weight: 83 kDa

Gene ID: 57787

NCBI Accession: NP_001186796

UniProt: Q96L34