RGS12 antibody (C-Term)

Catalog No. ABIN5516146

The Rabbit Polyclonal anti-RGS12 antibody is suitable to detect RGS12 in samples from Human. It has been validated for WB.

Quick Overview for RGS12 antibody (C-Term) (ABIN5516146)

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS12 Antibody

Binding Specificity: C-Term

Sequence: STLLPPPSTP QEVPGPSRPG SGTHGSRDLP VNRIIDVDLV TGSAPGRDGG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS12

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Alternative Name: RGS12

Background: This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.

Protein Size: 167

Gene ID: 6002

NCBI Accession: NM_002926, NP_002917

UniProt: O14924

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling