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NLRP12 antibody (N-Term)
NLRP12
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NLRP12 Antibody
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Target
See all NLRP12 Antibodies
NLRP12
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Binding Specificity
All epitopes for NLRP12 antibodies
N-Term
Reactivity
Human, Mouse, Rat, Cow, Pig, Dog
Host
All hosts for NLRP12 antibodies
Rabbit
Clonality
All clonalities for NLRP12 antibodies
Polyclonal
Conjugate
All conjugates for NLRP12 antibodies
This NLRP12 antibody is un-conjugated
Application
All applications for NLRP12 antibodies
Western Blotting (WB)
Sequence
LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV
Predicted Reactivity
Cow: 100%, Dog: 90%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 85%
Characteristics
This is a rabbit polyclonal antibody against NLRP12. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human NLRP12
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for NLRP12
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Target
NLRP12
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Alternative Name
NLRP12 (NLRP12 Products )
Synonyms
Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
Background
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. Alias Symbols: NLRP12, NALP12, PYPAF7, RNO, Protein Interaction Partner: Dlg4, HSP90AA1, HSPA8, HSPA4, FAF1, IRAK1, PYCARD, Protein Size: 1061
Gene ID
91662
NCBI Accession
NP_653288
UniProt
P59046
Pathways
Positive Regulation of Endopeptidase Activity , Inflammasome
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