BSND antibody (Middle Region)

Catalog No. ABIN5516480

The Rabbit Polyclonal anti-BSND antibody (ABIN5516480) specifically detects BSND. The antibody is reactive with Human and Pig samples.

Quick Overview for BSND antibody (Middle Region) (ABIN5516480)

Target: BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSND antibody is un-conjugated

Application: Please inquire

Product Details anti-BSND Antibody

Binding Specificity: Middle Region

Purpose: BSND Antibody - middle region

Sequence: PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD

Predicted Reactivity: Human: 100%, Pig: 77%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BSND

Application Details

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59579-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BSND

Target: BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))

Alternative Name: BSND

Background:

Background Information: This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness.

Gene Name: barttin CLCNK type accessory beta subunit

Alternative Symbols: BART, DFNB73

Protein Name: barttin

Molecular Weight: 35 kDa

Gene ID: 7809

NCBI Accession: NP_476517

UniProt: Q8WZ55

Pathways: Sensory Perception of Sound