CD1c antibody (C-Term)

Catalog No. ABIN5516504

The Rabbit Polyclonal anti-CD1c antibody (ABIN5516504) specifically detects CD1c in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for CD1c antibody (C-Term) (ABIN5516504)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1c antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1c Antibody

Binding Specificity: C-Term

Purpose: CD1C Antibody - C-terminal region

Sequence: ASGFYPKPVW VTWMRNEQEQ LGTKHGDILP NADGTWYLQV ILEVASEEPA

Predicted Reactivity: Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CD1C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63373-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1C

Background:

Background Information: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Alternative Symbols: R7, CD1, CD1A, BDCA1

Protein Name: T-cell surface glycoprotein CD1c

Molecular Weight: 35kDa

Gene ID: 911

NCBI Accession: NP_001756

UniProt: P29017