DGKG antibody (C-Term)

Catalog No. ABIN5516630

The Rabbit Polyclonal anti-DGKG antibody (ABIN5516630) specifically detects DGKG in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for DGKG antibody (C-Term) (ABIN5516630)

Target: DGKG (DAG Kinase gamma)

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGKG Antibody

Binding Specificity: C-Term

Purpose: DGKG Antibody - C-terminal region

Sequence: KLLPMQVDGE PWMQPCCTIK ITHKNQAPMM MGPPQKSSFF SLRRKSRSKD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DGKG. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGKG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59761-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DGKG

Target: DGKG (DAG Kinase gamma)

Alternative Name: DGKG

Background:

Background Information: This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: diacylglycerol kinase, gamma 90 kDa

Alternative Symbols: DAGK3, DGK-GAMMA

Protein Name: Diacylglycerol kinase gamma

Molecular Weight: 82 kDa

Gene ID: 1608

UniProt: P49619