HPR antibody (C-Term)

Catalog No. ABIN5516879

The Rabbit Polyclonal anti-HPR antibody (ABIN5516879) specifically detects HPR in WB. The antibody is reactive with Human samples.

Quick Overview for HPR antibody (C-Term) (ABIN5516879)

Target: HPR (Haptoglobin Related Protein (HPR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HPR Antibody

Binding Specificity: C-Term

Purpose: HPR Antibody - C-terminal region

Sequence: CLPSKNYAEV GRVGYVSGWG QSDNFKLTDH LKYVMLPVAD QYDCITHYEG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against HPR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HPR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42576-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HPR

Target: HPR (Haptoglobin Related Protein (HPR))

Alternative Name: HPR

Background:

Background Information: This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.

Gene Name: haptoglobin-related protein

Alternative Symbols: HP, A-259H10.2

Protein Name: Haptoglobin-related protein

Molecular Weight: 38kDa

Gene ID: 3250

UniProt: P00739

Pathways: Response to Water Deprivation