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Leupaxin antibody (C-Term)
LPXN
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Leupaxin Antibody
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Target
See all Leupaxin (LPXN) Antibodies
Leupaxin (LPXN)
Binding Specificity
All epitopes for Leupaxin antibodies
C-Term
Reactivity
All reactivities for Leupaxin antibodies
Human
Host
All hosts for Leupaxin antibodies
Rabbit
Clonality
All clonalities for Leupaxin antibodies
Polyclonal
Conjugate
All conjugates for Leupaxin antibodies
This Leupaxin antibody is un-conjugated
Application
All applications for Leupaxin antibodies
Western Blotting (WB)
Sequence
HGCGQPITGR CISAMGYKFH PEHFVCAFCL TQLSKGIFRE QNDKTYCQPC
Characteristics
This is a rabbit polyclonal antibody against LPXN. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPXN
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Leupaxin
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Target
Leupaxin (LPXN)
Alternative Name
LPXN (LPXN Products )
Synonyms
LDPL antibody, 4933402K05Rik antibody, A530083L21Rik antibody, AV278559 antibody, MGC140379 antibody, leupaxin antibody, hypothetical protein antibody, Leupaxin antibody, LPXN antibody, Lpxn antibody, lpxn antibody, PAAG_03110 antibody, PGTG_11441 antibody
Background
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Alias Symbols: LPXN, LDLP, Protein Interaction Partner: LMO1, HOXC9, RUNX1T1, TXLNB, PLEKHH2, PLEKHN1, SFI1, NDN, SUMO1, UBC, NEDD8, HOXA1, ZNF175, MAP2K7, HDAC6, PTK2, MAPK6, IKBKG, ZNF426, IMP3, POM121, PHF21A, LIMS1, PTK2B, PTPN12, ITGA4, Protein Size: 386
Gene ID
9404
NCBI Accession
NP_004802
UniProt
O60711
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