CAPG antibody (N-Term)

Catalog No. ABIN5517091

The Rabbit Polyclonal anti-CAPG antibody is suitable to detect CAPG in samples from Human. It has been validated for WB.

Quick Overview for CAPG antibody (N-Term) (ABIN5517091)

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAPG Antibody

Binding Specificity: N-Term

Purpose: CAPG Antibody - N-terminal region

Sequence: YTAIPQSGSP FPGSVQDPGL HVWRVEKLKP VPVAQENQGV FFSGDSYLVL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75972-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPG

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Alternative Name: CAPG

Background:

Background Information: This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.

Gene Name: Capping protein (actin filament), gelsolin-like

Alternative Symbols: MCP, AFCP, HEL-S-66

Protein Name: macrophage-capping protein

Molecular Weight: 38 kDa

Gene ID: 822

NCBI Accession: NP_001243068

UniProt: P40121

Pathways: Regulation of Actin Filament Polymerization