TMEM67 antibody (C-Term)

Catalog No. ABIN5517188

The Rabbit Polyclonal anti-TMEM67 antibody (ABIN5517188) specifically detects TMEM67 in WB. The antibody is reactive with Human samples.

Quick Overview for TMEM67 antibody (C-Term) (ABIN5517188)

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM67 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM67 Antibody

Binding Specificity: C-Term

Purpose: TMEM67 Antibody - C-terminal region

Sequence: FDLLFFCVVD LACQNFILAS FLTYLQQEIF RYIRNTVGQK NLASKTLVDQ

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM67

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78321-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMEM67

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Alternative Name: TMEM67

Background:

Background Information: The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).

Gene Name: transmembrane protein 67

Alternative Symbols: MKS3, JBTS6, NPHP11, TNEM67, MECKELIN

Protein Name: meckelin

Molecular Weight: 109 kDa

Gene ID: 91147

NCBI Accession: NP_001135773

UniProt: Q5HYA8