VANGL2 antibody (N-Term)

Catalog No. ABIN5517379

The Rabbit Polyclonal anti-VANGL2 antibody is suitable to detect VANGL2 in samples from Human. It has been validated for WB.

Quick Overview for VANGL2 antibody (N-Term) (ABIN5517379)

Target: VANGL2 (Vang-Like 2 (VANGL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VANGL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VANGL2 Antibody

Binding Specificity: N-Term

Purpose: VANGL2 Antibody - N-terminal region

Sequence: SSRKHRDRRD RHRSKSRDGG RGDKSVTIQA PGEPLLDNES TRGDERDDNW

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VANGL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78136-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Alternative Name: VANGL2

Background:

Background Information: The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

Gene Name: VANGL planar cell polarity protein 2

Alternative Symbols: LPP1, LTAP, STB1, STBM, STBM1

Protein Name: vang-like protein 2

Molecular Weight: 60 kDa

Gene ID: 57216

NCBI Accession: NP_065068

UniProt: Q9ULK5

Pathways: WNT Signaling, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization